To improve the performance of the afterburner for the turbofan engine, an innovative type of mixer, namely, the chevron mixer, was considered to enhance the mixture between the core flow and the bypass flow. Computational fluid dynamics (CFD) simulations investigated the aerodynamic performances and combustion characteristics of the chevron mixer inside a typical afterburner. Three types of mixer, namely, CC (chevrons tilted into core flow), CB (chevrons tilted into bypass flow), and CA (chevrons tilted into core flow and bypass flow alternately), respectively, were studied on the aerodynamic performances of mixing process. The chevrons arrangement has significant effect on the mixing characteristics and the CA mode seems to be advantageous for the generation of the stronger streamwise vortices with lower aerodynamic loss. Further investigations on combustion characteristics for CA mode were performed. Calculation results reveal that the local temperature distribution at the leading edge section of flame holder is improved under the action of streamwise vortices shedding from chevron mixers. Consequently, the combustion efficiency increased by 3.5% compared with confluent mixer under the same fuel supply scheme.