Accurate structural modeling of blisk mistuning is critical for the analysis of forced response in turbomachinery. Apart from intentional mistuning, mistuning can be due to the manufacturing tolerances, corrosion, foreign object damage, and in-service wear in general. It has been shown in past studies that mistuning can increase the risk of blade failure due to energy localization. For weak blade to blade coupling, this localization has been shown to be critical and higher amplitudes of vibration are expected in few blades. This paper presents a comparison of three reduced order models (ROMs) for the structural modeling of blisks. Two of the models assume cyclic symmetry, while the third model is free of this assumption. The performance of the reduced order models for cases with small and large amount of mistuning will be examined. The benefits and drawbacks of each reduction method will be discussed.