The power generation industry is targeting heavy duty gas turbine to increase power and efficiency. Hot gas temperature and massflow are continuously being increased. It brings new challenges for the design of cooling systems for turbine blades and vanes. Up to date most of studies of heat transfer in internal cooling channels were in the range of Reynolds numbers below 80,000 for cooling air flow, for example, experimental series done by J. Chin Han et al. since 1985. Actually the range of Reynolds numbers is increased with the increase of total massflow. Extrapolation of available data is not reliable while local distribution of heat transfer coefficients becomes critical in terms of thermal stresses. Only few recent studies deal with the range of Reynolds number above 80,000, for example, in 2009 J. Chin et. al showed results for 45° angled ribs provided only area averaged values for heat transfer coefficient over one pitch and in 2003 R. Bunker showed local distribution for 45° angled ribs only. Within current study the experimental measurements of local heat transfer and friction in ribbed cooling channel were performed for Reynolds numbers in range of 100,000 – 180,000, what fits the parameters of modern and perspective heavy duty gas turbines. Using thermochromic liquid crystal technology the following rib configurations were tested: angled 45°, 60°, 90° and chevron 45°, 60°; pitch to height ratio of 10; rib turbulator height-to-channel hydraulic diameter ratio of 0.083. Maximum averaged heat transfer value was provided by 60° angled ribs. Comparison of local distribution of heat transfer coefficients for considered configurations was performed. Minimum non-uniformness of heat transfer coefficient was provided by chevron ribs, having maximum friction factor. Conjugated thermal-hydraulic analysis for cooled vane for heavy duty gas turbine was performed in order to quantify the effect of local heat transfer coefficient distribution in ribbed cooling channel. Metal temperature calculation was performed for two cases of air side thermal boundary condition application for wall surface between rib-turbulators: averaged value of heat transfer coefficient and detailed local distribution. Comparison of calculated metal temperature for 2 cases shows that usage of locally distributed air side heat transfer coefficient is important and should increase the accuracy of temperature prediction by 50°C. Consideration of local distribution of heat transfer coefficient is important for cooling design of modern heavy duty gas turbine in order to provide acceptable thermal gradients and consequently reach lifetime targets.