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Journal Articles

Announcing the 2022 Richard Skalak Award Editors' Choice Papers

C. Ross Ethier, Thao D. Nguyen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Editorial
J Biomech Eng. September 2024, 146(9): 090201.
Paper No: BIO-24-1033
https://doi.org/10.1115/1.4065051
Published Online: April 8, 2024
View Article titled, Announcing the 2022 Richard Skalak Award Editors' Choice Papers
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Topics: Bearings, Bioengineering, Biomechanical engineering, Biomechanics, Biomedical engineering, Cancer, Computational fluid dynamics, Computer simulation, Dosimetry, Engineering disciplines
Journal Articles

A Novel Port to Facilitate Magnetic Hyperthermia Therapy for Glioma

Benjamin Rodriguez, Peter Campbell, Joseph Borrello, Ian Odland, Tyree Williams, Eugene I. Hrabarchuk, Tirone Young, Anirudh Sharma, Alexander J. Schupper, Benjamin Rapoport, Robert Ivkov, Constantinos Hadjipanayis
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2024, 146(1): 011009.
Paper No: BIO-23-1207
https://doi.org/10.1115/1.4063556
Published Online: November 22, 2023
View Article titled, A Novel Port to Facilitate Magnetic Hyperthermia Therapy for Glioma
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Topics: Brain, Design, Iron, Nanoparticles, Patient treatment, Phantoms, Physiology, Tumors, Temperature, Biological tissues
Journal Articles

Biomechanical Response of Cancer Stem Cells to Low-Intensity Ultrasound

Yaozhang Yang, Meng Du, Jinsui Yu, Zhiyi Chen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2023, 145(9): 091001.
Paper No: BIO-21-1438
https://doi.org/10.1115/1.4062299
Published Online: May 22, 2023
View Article titled, Biomechanical Response of Cancer Stem Cells to Low-Intensity Ultrasound
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Topics: Cancer, Stem cells, Ultrasound, Drugs, Biomechanics, Stiffness
Journal Articles

Data-Driven Simulation of Fisher–Kolmogorov Tumor Growth Models Using Dynamic Mode Decomposition

Alex Viguerie, Malú Grave, Gabriel F. Barros, Guillermo Lorenzo, Alessandro Reali, Alvaro L. G. A. Coutinho
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2022, 144(12): 121001.
Paper No: BIO-22-1059
https://doi.org/10.1115/1.4054925
Published Online: August 19, 2022
View Article titled, Data-Driven Simulation of Fisher–Kolmogorov Tumor Growth Models Using Dynamic Mode Decomposition
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Topics: Simulation, Tumors, Errors, Computer simulation, Cancer
Journal Articles

The Elephant in the Cell: Nuclear Mechanics and Mechanobiology

Michelle L. Jones, Kris Noel Dahl, Tanmay P. Lele, Daniel E. Conway, Vivek Shenoy, Soham Ghosh, Spencer E. Szczesny
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Review Articles
J Biomech Eng. August 2022, 144(8): 080802.
Paper No: BIO-21-1401
https://doi.org/10.1115/1.4053797
Published Online: March 11, 2022
View Article titled, The Elephant in the Cell: Nuclear Mechanics and Mechanobiology
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Topics: Biological tissues, Computer simulation, Deformation, Mechanical properties, Mechanobiology, Modeling, Proteins, Shapes, Tension, Stress
Journal Articles

Experimental and Numerical Investigation of Parameters Affecting High-Frequency Irreversible Electroporation for Prostate Cancer Ablation

Kenneth N. Aycock, Ram Anand Vadlamani, Edward J. Jacobs, IV, Khan Mohammad Imran, Scott S. Verbridge, Irving C. Allen, Navid Manuchehrabadi, Rafael V. Davalos
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2022, 144(6): 061003.
Paper No: BIO-21-1372
https://doi.org/10.1115/1.4053595
Published Online: February 15, 2022
View Article titled, Experimental and Numerical Investigation of Parameters Affecting High-Frequency Irreversible Electroporation for Prostate Cancer Ablation
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Topics: Ablation (Vaporization technology), Biological tissues, Cancer, Damage, Delays, Electric fields, Electroporation, Fire, Tumors, Performance
Includes: Supplementary data
Journal Articles

Confined Cell Migration and Asymmetric Hydraulic Environments to Evaluate the Metastatic Potential of Cancer Cells

Yago Juste-Lanas, Pedro Enrique Guerrero, Daniel Camacho-Gómez, Silvia Hervás-Raluy, Jose M. García-Aznar, María J. Gomez-Benito
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. July 2022, 144(7): 074502.
Paper No: BIO-21-1259
https://doi.org/10.1115/1.4053143
Published Online: February 15, 2022
View Article titled, Confined Cell Migration and Asymmetric Hydraulic Environments to Evaluate the Metastatic Potential of Cancer Cells
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Topics: Cancer, Microfluidics, Tumors
Includes: Supplementary data
Journal Articles

Quasi-Linear Viscoelastic Characterization of Soft Tissue-Mimicking Materials

Hamed Helisaz, Mattia Bacca, Mu Chiao
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2021, 143(6): 061007.
Paper No: BIO-20-1346
https://doi.org/10.1115/1.4050036
Published Online: March 15, 2021
View Article titled, Quasi-Linear Viscoelastic Characterization of Soft Tissue-Mimicking Materials
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Topics: Biological tissues, Phantoms, Relaxation (Physics), Stress, Cancer, Compression, Fittings, Young's modulus, Elastomers, Elasticity
Journal Articles

Thermal Simulations of Cancerous Breast Tumors and Cysts on a Realistic Female Torso

Francisco Javier González
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2021, 143(6): 061001.
Paper No: BIO-19-1463
https://doi.org/10.1115/1.4049957
Published Online: March 9, 2021
View Article titled, Thermal Simulations of Cancerous Breast Tumors and Cysts on a Realistic Female Torso
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Topics: Cancer, Simulation, Temperature, Thermography, Tumors, Biological tissues, Skin, Finite element analysis, Heat transfer, Infrared imaging
Journal Articles

Multiscale Computational Fluid Dynamics Modeling for Personalized Liver Cancer Radioembolization Dosimetry

Amirtahà Taebi, Catherine T. Vu, Emilie Roncali
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2021, 143(1): 011002.
Paper No: BIO-19-1356
https://doi.org/10.1115/1.4047656
Published Online: September 30, 2020
View Article titled, Multiscale Computational Fluid Dynamics Modeling for Personalized Liver Cancer Radioembolization Dosimetry
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Topics: Computational fluid dynamics, Dosimetry, Flow (Dynamics), Liver, Tumors, Cancer, Blood flow
Includes: Supplementary data
Journal Articles

The Effects of Stiffness, Fluid Viscosity, and Geometry of Microenvironment in Homeostasis, Aging, and Diseases: A Brief Review

Seungman Park, Wei-Hung Jung, Matthew Pittman, Junjie Chen, Yun Chen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Review Articles
J Biomech Eng. October 2020, 142(10): 100804.
Paper No: BIO-20-1105
https://doi.org/10.1115/1.4048110
Published Online: August 31, 2020
View Article titled, The Effects of Stiffness, Fluid Viscosity, and Geometry of Microenvironment in Homeostasis, Aging, and Diseases: A Brief Review
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Topics: Stiffness, Viscosity, Fluids, Diseases, Cancer
Journal Articles

The Role of Fluid Shear and Metastatic Potential in Breast Cancer Cell Migration

Brandon D. Riehl, Eunju Kim, Jeong Soon Lee, Bin Duan, Ruiguo Yang, Henry J. Donahue, Jung Yul Lim
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2020, 142(10): 101001.
Paper No: BIO-18-1130
https://doi.org/10.1115/1.4047076
Published Online: July 8, 2020
View Article titled, The Role of Fluid Shear and Metastatic Potential in Breast Cancer Cell Migration
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Topics: Cancer, Flow (Dynamics), Fluids, Shear (Mechanics), Displacement
Includes: Supplementary data
Journal Articles

Numerical Simulation of the Heat Transfer in the Cryoprobe of an Innovative Apparatus for Cryosurgery

Barbara Bosio, Dario Bove, Lorenzo Guidetti, Leopoldo Avalle, Elisabetta Arato
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2019, 141(1): 011008.
Paper No: BIO-18-1192
https://doi.org/10.1115/1.4041526
Published Online: October 17, 2018
View Article titled, Numerical Simulation of the Heat Transfer in the Cryoprobe of an Innovative Apparatus for Cryosurgery
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Topics: Biological tissues, Fluids, Geometry, Heat transfer, Pressure, Probes, Simulation, Temperature, Computer software, Ethanol
Journal Articles

Mathematical Model for Tissue-Level Hypoxic Response in Microfluidic Environment

Adnan Morshed, Prashanta Dutta
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2018, 140(1): 011009.
Paper No: BIO-17-1090
https://doi.org/10.1115/1.4037915
Published Online: November 9, 2017
View Article titled, Mathematical Model for Tissue-Level Hypoxic Response in Microfluidic Environment
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Topics: Biological tissues, Microfluidics, Oxygen, Cancer
Includes: Supplementary data
Journal Articles

Separation of Solid Stress From Interstitial Fluid Pressure in Pancreas Cancer Correlates With Collagen Area Fraction

Michael D. Nieskoski, Kayla Marra, Jason R. Gunn, Stephen C. Kanick, Marvin M. Doyley, Tayyaba Hasan, Stephen P. Pereira, B. Stuart Trembly, Brian W. Pogue
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2017, 139(6): 061002.
Paper No: BIO-16-1409
https://doi.org/10.1115/1.4036392
Published Online: April 18, 2017
View Article titled, Separation of Solid Stress From Interstitial Fluid Pressure in Pancreas Cancer Correlates With Collagen Area Fraction
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Topics: Biological tissues, Fluid pressure, Pressure, Stress, Tumors, Catheters, Cancer
Includes: Supplementary data
Journal Articles

The Solid Mechanics of Cancer and Strategies for Improved Therapy

Triantafyllos Stylianopoulos
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2017, 139(2): 021004.
Paper No: BIO-16-1230
https://doi.org/10.1115/1.4034991
Published Online: January 19, 2017
View Article titled, The Solid Mechanics of Cancer and Strategies for Improved Therapy
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Topics: Cancer, Stress, Tumors, Biological tissues, Solid mechanics, Patient treatment
Journal Articles

Single-Cell Migration in Complex Microenvironments: Mechanics and Signaling Dynamics

Michael Mak, Fabian Spill, Roger D. Kamm, Muhammad H. Zaman
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2016, 138(2): 021004.
Paper No: BIO-15-1478
https://doi.org/10.1115/1.4032188
Published Online: January 27, 2016
View Article titled, Single-Cell Migration in Complex Microenvironments: Mechanics and Signaling Dynamics
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Topics: Cancer, Dynamics (Mechanics), Flow (Dynamics), Geometry, Machinery, Physiology, Polarization (Electricity), Polarization (Light), Polarization (Waves), Stiffness
Journal Articles

In Memory of Robert L. Spilker

Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Guest Editorial
J Biomech Eng. August 2013, 135(8): 080301.
Paper No: BIO-13-1204
https://doi.org/10.1115/1.4024756
Published Online: June 14, 2013
View Article titled, In Memory of Robert L. Spilker
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Topics: Algorithms, Biomechanics, Biomedical engineering, Cancer, Cartilage, Deformation, Engineering teachers, Finite element analysis, Modeling, Soft tissues
Journal Articles

Finite Element Analysis of Traction Force Microscopy: Influence of Cell Mechanics, Adhesion, and Morphology

Rachel Zielinski, Cosmin Mihai, Douglas Kniss, Samir N. Ghadiali
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2013, 135(7): 071009.
Paper No: BIO-12-1619
https://doi.org/10.1115/1.4024467
Published Online: June 11, 2013
View Article titled, Finite Element Analysis of Traction Force Microscopy: Influence of Cell Mechanics, Adhesion, and Morphology
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Topics: Adhesion, Finite element analysis, Stiffness, Stress, Traction, Microscopy, Sensitivity analysis, Cellular mechanics, Cancer
Journal Articles

Advances in Finite Element Simulations of Elastosonography for Breast Lesion Detection

Simona Celi, Francesca Di Puccio, Paola Forte
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. August 2011, 133(8): 081006.
https://doi.org/10.1115/1.4004491
Published Online: September 6, 2011
View Article titled, Advances in Finite Element Simulations of Elastosonography for Breast Lesion Detection
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Topics: Biological tissues, Cancer, Finite element analysis, Friction, Phantoms, Sensitivity analysis, Simulation, Tumors, Deformation, Elastic moduli