...Geunseon Ahn; Jeong Hun Park; Taeyun Kang; Jin Woo Lee; Hyun-Wook Kang; Dong-Woo Cho The aim of this study was to maximize oxygen diffusion within a three-dimensional scaffold in order to improve cell viability and proliferation. To evaluate the effect of pore architecture on oxygen diffusion, we...

...Kazuto Masamoto; Kazuo Tanishita Oxygen is essential to maintaining normal brain function. A large body of evidence suggests that the partial pressure of oxygen ( p O 2 ) in brain tissue is physiologically maintained within a narrow range in accordance with region-specific brain activity. Since...

... the structure, chemical components, and water content in IVD, but to our knowledge no study has investigated the effect of mechanical loading on oxygen transport in IVD. The objective of this study was to determine the strain-dependent behavior of oxygen diffusivity in IVD tissue. A one-dimensional steady-state...

... control systems molecular biophysics oxygen vascular perfusion system PID control The precise simulation of arterial biomechanical conditions is of great importance in the field of vascular research. Our well established, validated ex vivo vascular perfusion system (EVPS) has been used...

...Ohwon Kwon; Mahesh Krishnamoorthy; Young I. Cho; John M. Sankovic; Rupak K. Banerjee The effect of blood viscosity on oxygen transport in a stenosed coronary artery during the postangioplasty scenario is studied. In addition to incorporating varying blood viscosity using different hematocrit (Hct...

...Jennifer R. Zierenberg; Hideki Fujioka; Ronald B. Hirschl; Robert H. Bartlett; James B. Grotberg The fundamental study of blood flow past a circular cylinder filled with an oxygen source is investigated as a building block for an artificial lung. The Casson constitutive equation is used to describe...

...K. T. Moorhead; J. G. Chase; T. David; J. Arnold The Circle of Willis (CoW) is a ringlike structure of blood vessels found at the base of the brain. Its main function is to distribute oxygen-rich arterial blood to the cerebral mass. In a previous study, a one-dimensional (1D) model of the CoW...

...D. Mokhbi Soukane; A. Shirazi-Adl; J. P. G. Urban The transport of oxygen and lactate (i.e., lactic acid) in the human intervertebral disc was investigated accounting for the measured coupling between species via the p H level in the tissue. Uncoupled cases were also analyzed to identify the extent...

...Jean-Luc Dulong; Cécile Legallais A sphere within a cylinder representing the islet encapsulated in a hollow fiber can model an implantable bioartificial pancreas. Based on a finite element model for insulin response to a glucose load in the presence of various oxygen supplies, the present study...

...Bram G. Sengers; Hannah K. Heywood; David A. Lee; Cees W. J. Oomens; Dan L. Bader A combined experimental-numerical approach was adopted to characterize glucose and oxygen uptake and lactate production by bovine articular chondrocytes in a model system. For a wide range of cell concentrations...

...Vinod Suresh; Joseph C. Anderson; James B. Grotberg; Ronald B. Hirschl In partial liquid ventilation (PLV), perfluorocarbon (PFC) acts as a diffusion barrier to gas transport in the alveolar space since the diffusivities of oxygen and carbon dioxide in this medium are four orders of magnitude lower...

...Amador M. Guzmán; Rodrigo A. Escobar; Cristina H. Amon Computational investigations of flow mixing and oxygen transfer characteristics in an intravenous membrane oxygenator (IMO) are performed by direct numerical simulations of the conservation of mass, momentum, and species equations. Three...

...H. Hangan; S. Bekele The flow and concentration fields for various medical oxygen delivery devices are numerically investigated. Simulations are performed for a classical Venturi mask and two new OxyArm portable devices. The velocity and oxygen concentration fields are investigated for: (i...

... 12 2002 oxygen solutions blood bubbles blood vessels nucleation biomedical engineering This paper describes a strategy for the rapid delivery of large quantities of dissolved oxygen to the bloodstream without the formation of oxygen gas bubbles. The potential method benefits...

...Monica Y. Garcia; Brack G. Hattler; William J. Federspiel Intravena caval respiratory support (or membrane oxygenation) is a potential therapy for patients with acute respiratory insufficiency. A respiratory support catheter is being developed that consists of a bundle of hollow fiber membranes...

...Randall E. McClelland; Robin N. Coger Establishing suitable oxygen transport pathways within bioartificial liver replacement devices continues to be an important engineering challenge. Oxygen delivery is critical since this is one of the nutrients necessary to maintain hepatocyte viability...