A full-scale test bench for the analysis of frictional and modal behavior of nozzle guide vanes (NGV) is an advanced tool enabling high design accuracy for these components equipped with an increasing number of turbo-expanders. This subassembly is a key feature enabling operational flexibility for the expander. During the NGVs design, great attention must be paid to the natural frequencies of its kinematic chain, which are influenced by internal clearances and by friction. In this paper, the results of a testing campaign performed on an NGV assembly employing realistic blade geometry are presented together with details concerning the test bench commissioning and setup procedure. The testing campaign involves three different combinations of blade orientation and preload corresponding to typical design conditions of the expander. In addition, two bushing clearance values corresponding to different worn-out conditions were investigated. The measurements of the global friction coefficient based on actuator force detection are summarized. After that, the reconstruction of mode shapes based on experimental modal analysis is explained. The results highlight the importance of loading conditions on the actual value of friction force and their influence on blade natural frequencies. The testing campaign was used to properly validate finite element models to be used for further investigations.