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Ajit P. Yoganathan
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Proceedings Papers

Analysis of Fluid Mechanical Energy Losses in Aortic Valve Stenosis

Russell S. Heinrich, Arnold A. Fontaine, Randall Y. Grimes, Kristin E. Moore, Robert A. Levine, Ajit P. Yoganathan
Proc. ASME. IMECE96, Advances in Bioengineering, 193-194, November 17–22, 1996
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1996-1180
https://doi.org/10.1115/IMECE1996-1180
View Paper titled, Analysis of Fluid Mechanical Energy Losses in Aortic Valve Stenosis
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Topics: Energy dissipation, Fluid mechanics, Valves, Pressure drop, Blood flow, Catheters, Energy (Physics), Pressure, Pressure gradient, Stress
Proceedings Papers

Insights Into the Formation and Characteristics of Leakage Flow Structures Through Bileaflet Mechanical Heart Valve Prostheses

Jeffrey T. Ellis, Timothy M. Healy, Arnold A. Fontaine, Rahul Saxena, Ajit P. Yoganathan
Proc. ASME. IMECE96, Advances in Bioengineering, 279-280, November 17–22, 1996
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1996-1223
https://doi.org/10.1115/IMECE1996-1223
View Paper titled, Insights Into the Formation and Characteristics of Leakage Flow Structures Through Bileaflet Mechanical Heart Valve Prostheses
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Topics: Heart valve prostheses, Leakage flows, Prostheses, Flow (Dynamics), Valves, Hinges, Blood, Jets, Leakage, Pressure gradient
Proceedings Papers

Computational Simulations of the Flow Convergence Method for the Quantification of Mitral Regurgitation: Comparison of Fluent and CFD-ACE

Joanne Hopmeyer, Patrick W. Wilkerson, Robert A. Levine, Ajit P. Yoganathan
Proc. ASME. IMECE96, Advances in Bioengineering, 283-284, November 17–22, 1996
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1996-1225
https://doi.org/10.1115/IMECE1996-1225
View Paper titled, Computational Simulations of the Flow Convergence Method for the Quantification of Mitral Regurgitation: Comparison of Fluent and CFD-ACE
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Topics: Computational fluid dynamics, Engineering simulation, Flow (Dynamics), Simulation, Diseases, Blood, Valves
Proceedings Papers

Left Ventricular Flow Visualization by Magnetic Resonance Velocity Mapping

Sylvain F. Milet, Peter G. Walker, Kim Houlind, W. Yong Kim, Erik M. Pedersen, Ajit P. Yoganathan
Proc. ASME. IMECE96, Advances in Bioengineering, 461-462, November 17–22, 1996
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1996-1314
https://doi.org/10.1115/IMECE1996-1314
View Paper titled, Left Ventricular Flow Visualization by Magnetic Resonance Velocity Mapping
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Topics: Flow visualization, Magnetic resonance, Ultrasound, Cardiac cycle, Flow (Dynamics), Flow measurement, Velocity measurement, Visualization
Journal Articles

Effect of Leaflet Type and Leaflet-Stent Attachment Height on Transcatheter Aortic Valve Leaflet Thrombosis Potential

Beatrice E. Ncho, Andrew W. Siefert, Vahid Sadri, Jillian Ortner, Ajit P. Yoganathan
Journal: Journal of Medical Devices
Publisher: ASME
Article Type: Research-Article
J. Med. Devices. June 2022, 16(2): 021005.
Paper No: MED-21-1136
https://doi.org/10.1115/1.4052902
Published Online: February 3, 2022
View Article titled, Effect of Leaflet Type and Leaflet-Stent Attachment Height on Transcatheter Aortic Valve Leaflet Thrombosis Potential
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Topics: Flow (Dynamics), Kinematics, Valves, Thrombosis, Stents, Particulate matter, Cardiac cycle
Includes: Supplementary data
Proceedings Papers

Three-Dimensional Cardiac Models With Fluid-Structure Interaction: Application of the Immersed Boundary Method at Physiologic Reynolds Numbers

Jack D. Lemmon, Jr., Ajit P. Yoganathan
Proc. ASME. IMECE98, Advances in Bioengineering, 73-74, November 15–20, 1998
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1998-0036
https://doi.org/10.1115/IMECE1998-0036
View Paper titled, Three-Dimensional Cardiac Models With Fluid-Structure Interaction: Application of the Immersed Boundary Method at Physiologic Reynolds Numbers
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Topics: Fluid structure interaction, Physiology, Reynolds number, Biological tissues, Blood, Fluids, Pressure, Annulus, Computational methods, Engineering simulation
Proceedings Papers

The Effect of Bileaflet Prosthetic Heart Valve Orifice Area on Differences in Distal Flow Characteristics

Brandon R. Travis, Jeffrey T. Ellis, Rahul Saxena, Ajit P. Yoganathan
Proc. ASME. IMECE98, Advances in Bioengineering, 71-72, November 15–20, 1998
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1998-0035
https://doi.org/10.1115/IMECE1998-0035
View Paper titled, The Effect of Bileaflet Prosthetic Heart Valve Orifice Area on Differences in Distal Flow Characteristics
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Topics: Flow (Dynamics), Heart valve prostheses, Valves, Thrombosis, Design, Shear stress, Turbulence, Blood, Platelets
Proceedings Papers

Research Contribution of Prosthetic Valve Manufacturers Interfacing Academic-Industry Research Efforts

Xiao Gong, Yi-Ren Woo, Ajit P. Yoganathan, Andreas Anayiotos
Proc. ASME. IMECE99, Advances in Bioengineering, 67, November 14–19, 1999
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1999-0380
https://doi.org/10.1115/IMECE1999-0380
View Paper titled, Research Contribution of Prosthetic Valve Manufacturers Interfacing Academic-Industry Research Efforts
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Topics: Artificial limbs, Valves, Design, Heart valve prostheses, Medical devices, Hemodynamics, Safety, Testing, Thrombosis
Journal Articles

In Memoriam Robert M. Nerem, 1937–2020

C. Ross Ethier, Colin G. Caro, Kenneth R. Diller, Robert E. Guldberg, Roger D. Kamm, Manu O. Platt, Ajit P. Yoganathan
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: In Memoriam
J Biomech Eng. June 2020, 142(6): 060101.
Paper No: BIO-20-1151
https://doi.org/10.1115/1.4046990
Published Online: April 30, 2020
View Article titled, In Memoriam Robert M. Nerem, 1937–2020
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Topics: Biomedicine, Engineering teachers, Mentoring, Biomechanical engineering, Biomedical engineering, Casting, Students
Journal Articles

On the Simulation of Mitral Valve Function in Health, Disease, and Treatment

Michael S. Sacks, Andrew Drach, Chung-Hao Lee, Amir H. Khalighi, Bruno V. Rego, Will Zhang, Salma Ayoub, Ajit P. Yoganathan, Robert C. Gorman, Joseph H., Gorman, III
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Review Articles
J Biomech Eng. July 2019, 141(7): 070804.
Paper No: BIO-18-1408
https://doi.org/10.1115/1.4043552
Published Online: June 3, 2019
View Article titled, On the Simulation of Mitral Valve Function in Health, Disease, and Treatment
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Topics: Biological tissues, Geometry, Simulation, Valves, Modeling, Fibers, Maintenance, Surgery, Stress
Journal Articles

Role of Mitral Annulus Diastolic Geometry on Intraventricular Filling Dynamics

Ikechukwu U. Okafor, Arvind Santhanakrishnan, Vrishank S. Raghav, Ajit P. Yoganathan
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2015, 137(12): 121007.
Paper No: BIO-15-1124
https://doi.org/10.1115/1.4031838
Published Online: November 3, 2015
View Article titled, Role of Mitral Annulus Diastolic Geometry on Intraventricular Filling Dynamics
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Topics: Annulus, Vortices, Geometry, Flow (Dynamics), Cardiac cycle, Design, Kinetic energy
Journal Articles

Population-Averaged Geometric Model of Mitral Valve From Patient-Specific Imaging Data

Andrew Drach, Amir H. Khalighi, Fleur M. ter Huurne, Chung-Hao Lee, Charles Bloodworth, Eric L. Pierce, Morten O. Jensen, Ajit P. Yoganathan, Michael S. Sacks
Journal: Journal of Medical Devices
Publisher: ASME
Article Type: Technical Briefs
J. Med. Devices. September 2015, 9(3): 030952.
Paper No: MED-15-1108
https://doi.org/10.1115/1.4030582
Published Online: September 1, 2015
View Article titled, Population-Averaged Geometric Model of Mitral Valve From Patient-Specific Imaging Data
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Topics: Geometry, Imaging, Valves, Shapes
Journal Articles

Design of a Pulsatile Flow Facility to Evaluate Thrombogenic Potential of Implantable Cardiac Devices

Sivakkumar Arjunon, Pablo Hidalgo Ardana, Neelakantan Saikrishnan, Shalv Madhani, Brent Foster, Ari Glezer, Ajit P. Yoganathan
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Design Innovation Paper
J Biomech Eng. April 2015, 137(4): 045001.
Paper No: BIO-14-1203
https://doi.org/10.1115/1.4029579
Published Online: April 1, 2015
View Article titled, Design of a Pulsatile Flow Facility to Evaluate Thrombogenic Potential of Implantable Cardiac Devices
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Topics: Blood, Cardiac cycle, Cardiovascular devices, Damage, Design, Flow (Dynamics), Pressure, Valves, Actuators, Platelets
Journal Articles

Blood Damage Through a Bileaflet Mechanical Heart Valve: A Quantitative Computational Study Using a Multiscale Suspension Flow Solver

B. Min Yun, Cyrus K. Aidun, Ajit P. Yoganathan
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2014, 136(10): 101009.
Paper No: BIO-13-1569
https://doi.org/10.1115/1.4028105
Published Online: August 12, 2014
View Article titled, Blood Damage Through a Bileaflet Mechanical Heart Valve: A Quantitative Computational Study Using a Multiscale Suspension Flow Solver
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Topics: Damage, Flow (Dynamics), Platelets, Simulation, Valves, Blood, Particulate matter, Modeling
Journal Articles

Effect of Hinge Gap Width of a St. Jude Medical Bileaflet Mechanical Heart Valve on Blood Damage Potential—An In Vitro Micro Particle Image Velocimetry Study

Brian H. Jun, Neelakantan Saikrishnan, Sivakkumar Arjunon, B. Min Yun, Ajit P. Yoganathan
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2014, 136(9): 091008.
Paper No: BIO-14-1006
https://doi.org/10.1115/1.4027935
Published Online: July 16, 2014
View Article titled, Effect of Hinge Gap Width of a St. Jude Medical Bileaflet Mechanical Heart Valve on Blood Damage Potential—An In Vitro Micro Particle Image Velocimetry Study
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Topics: Blood, Flow (Dynamics), Hinges, Valves, Damage, Leakage flows, Variable structure systems, Shear stress
Proceedings Papers

Non-Planar Shape of the Mitral Annulus Reduces Systolic Strain on the Posterior Leaflet by Increasing Leaflet Curvature

Muralidhar Padala, Michael S. Sacks, Ajit P. Yoganathan
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 139-140, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192996
https://doi.org/10.1115/SBC2008-192996
View Paper titled, Non-Planar Shape of the Mitral Annulus Reduces Systolic Strain on the Posterior Leaflet by Increasing Leaflet Curvature
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Topics: Annulus, Shapes, Valves, Cardiac cycle, Surgery
Proceedings Papers

Reduction of Flow-Induced Blood Damage in Bileaflet Mechanical Heart Valves Through Passive Flow Control

David W. Murphy, Lakshmi P. Dasi, Ari Glezer, Ajit P. Yoganathan
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 549-550, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192980
https://doi.org/10.1115/SBC2008-192980
View Paper titled, Reduction of Flow-Induced Blood Damage in Bileaflet Mechanical Heart Valves Through Passive Flow Control
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Topics: Blood, Damage, Flow (Dynamics), Flow control, Heart valve prostheses, Valves, Shear stress, Platelets, Vortices, Generators
Proceedings Papers

Multiscale Structural Analysis of Porcine Aortic Heart Valves Using a Collagen Fiber Network (CFN) Micromodel

Hee Sun Kim, Choon Hwai Yap, Lakshmi Prasad Dasi, Ajit P. Yoganathan, Rami Haj-Ali
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 451-452, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192800
https://doi.org/10.1115/SBC2008-192800
View Paper titled, Multiscale Structural Analysis of Porcine Aortic Heart Valves Using a Collagen Fiber Network (CFN) Micromodel
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Topics: Fibers, Structural analysis, Valves, Mechanical behavior, Anisotropy, Biological tissues, Deformation, Engineering simulation, Kinematics, Simulation
Proceedings Papers

Hemodynamic Energy Dissipation in the Cardiovascular System: Generalized Theoretical Analysis on Disease States

Lakshmi P. Dasi, Kerem Pekkan, Kartik S. Sundareswaran, Diane de Zelicourt, Resmi Krishnankutty, Pedro J. del Nido, Ajit P. Yoganathan
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 47-48, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192936
https://doi.org/10.1115/SBC2008-192936
View Paper titled, Hemodynamic Energy Dissipation in the Cardiovascular System: Generalized Theoretical Analysis on Disease States
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Topics: Cardiovascular system, Diseases, Energy dissipation, Hemodynamics, Theoretical analysis, Heart failure, Pressure
Proceedings Papers

Simulations of the Hinge Flow Fields of a Bileaflet Mechanical Heart Valve Under Physiologic Pulsatile Aortic Conditions

Hélène A. Simon, Liang Ge, Iman Borazjani, Fotis Sotiropoulos, Ajit P. Yoganathan
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 1093-1094, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192939
https://doi.org/10.1115/SBC2008-192939
View Paper titled, Simulations of the Hinge Flow Fields of a Bileaflet Mechanical Heart Valve Under Physiologic Pulsatile Aortic Conditions
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Topics: Engineering simulation, Flow (Dynamics), Heart valve prostheses, Hinges, Physiology, Simulation, Valves, Design, Blood, Hemodynamics