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Proceedings Papers

Characterization of Drug Delivery by a Novel Local Infusion Device

Elizabeth M. Lutostansky, David N. Ku, Christos Markou, Stephen Hanson
Proc. ASME. IMECE96, Advances in Bioengineering, 287-288, November 17–22, 1996
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1996-1227
https://doi.org/10.1115/IMECE1996-1227
View Paper titled, Characterization of Drug Delivery by a Novel Local Infusion Device
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Topics: Adhesion, Drug delivery systems, Drugs, Platelets, Thrombosis
Proceedings Papers

Effects of Upstream Curvature on Stenotic Flows

Harris L. Bergman, David N. Ku
Proc. ASME. IMECE96, Advances in Bioengineering, 189-190, November 17–22, 1996
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1996-1178
https://doi.org/10.1115/IMECE1996-1178
View Paper titled, Effects of Upstream Curvature on Stenotic Flows
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Topics: Flow (Dynamics), Bifurcation, Fluid mechanics, Physiology, Turbulence, Vessels
Proceedings Papers

Computational Simulation of Magnetic Resonance Angiograms in Stenotic Vessels: Effect of Stenosis Severity

Harris L. Bergman, John M. Siegel, John N. Oshinski, Roderic I. Pettigrew, David N. Ku
Proc. ASME. IMECE96, Advances in Bioengineering, 295-296, November 17–22, 1996
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1996-1231
https://doi.org/10.1115/IMECE1996-1231
View Paper titled, Computational Simulation of Magnetic Resonance Angiograms in Stenotic Vessels: Effect of Stenosis Severity
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Topics: Magnetic resonance, Simulation, Vessels, Signals, Ambiguity
Proceedings Papers

Convective Mass Transfer of ATP and Shear Stress in a 3-D Model of the Human Carotid Bifurcation

Elizabeth M. Lutostansky, David N. Ku
Proc. ASME. IMECE96, Advances in Bioengineering, 293-294, November 17–22, 1996
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1996-1230
https://doi.org/10.1115/IMECE1996-1230
View Paper titled, Convective Mass Transfer of ATP and Shear Stress in a 3-D Model of the Human Carotid Bifurcation
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Topics: Bifurcation, Mass transfer, Shear stress, Three-dimensional models, Atherosclerosis, Hemodynamics, Carotid arteries, Flow separation
Proceedings Papers

Numerical Study of Platelet Transport in Flowing Blood

Jerome Fiechter, David N. Ku
Proc. ASME. IMECE98, Advances in Bioengineering, 11-12, November 15–20, 1998
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1998-0006
https://doi.org/10.1115/IMECE1998-0006
View Paper titled, Numerical Study of Platelet Transport in Flowing Blood
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Topics: Blood, Platelets, Aneurysms, Convection, Diffusion (Physics), Laminar flow, Thrombosis, Turbulence
Proceedings Papers

Mechanistic Model of Arterial Thrombosis in Collagen-Coated Stenoses

David M. Wootton, Christos P. Markou, Stephen R. Hanson, David N. Ku
Proc. ASME. IMECE98, Advances in Bioengineering, 115-116, November 15–20, 1998
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1998-0057
https://doi.org/10.1115/IMECE1998-0057
View Paper titled, Mechanistic Model of Arterial Thrombosis in Collagen-Coated Stenoses
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Topics: Thrombosis, Platelets, Adhesion, Blood, Convection, Diffusion (Physics), Flow (Dynamics), Shear (Mechanics)
Proceedings Papers

Alterations in Endothelial Permeability After Intravascular Intervention

Naomi C. Chesler, Nathan Brewton, David N. Ku
Proc. ASME. IMECE98, Advances in Bioengineering, 369-370, November 15–20, 1998
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1998-0178
https://doi.org/10.1115/IMECE1998-0178
View Paper titled, Alterations in Endothelial Permeability After Intravascular Intervention
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Topics: Permeability, Catheters, Thrombosis, Wounds, Biomedicine, Carotid arteries, Cycles, Engineering prototypes, Pressure, Shear (Mechanics)
Proceedings Papers

Effects of Stenosis Asymmetry on Blood Flow in Stenotic Arteries and Wall Compression

Dalin Tang, Chun Yang, Zhongdan Huan, David N. Ku
Proc. ASME. IMECE99, Advances in Bioengineering, 75-76, November 14–19, 1999
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1999-0384
https://doi.org/10.1115/IMECE1999-0384
View Paper titled, Effects of Stenosis Asymmetry on Blood Flow in Stenotic Arteries and Wall Compression
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Topics: Blood flow, Compression, Flow (Dynamics), Pressure, Collapse, Deformation, Flutter (Aerodynamics), Rupture, Stress, Thrombosis
Proceedings Papers

Flow and Compression in Collapsible Asymmetric Stenosis Models of Arterial Disease

Shunichi Kobayashi, Takeshi Horie, Tomohito Amaya, Hirohisa Morikawa, Dalin Tang, David N. Ku
Proc. ASME. IMECE2001, Advances in Bioengineering, 283-284, November 11–16, 2001
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2001/BED-23141
https://doi.org/10.1115/IMECE2001/BED-23141
View Paper titled, Flow and Compression in Collapsible Asymmetric Stenosis Models of Arterial Disease
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Topics: Compression, Diseases, Flow (Dynamics), Collapse, Atherosclerosis, Blood, Blood flow, External pressure, Fluid pressure, Fracture (Materials)
Proceedings Papers

Axial Stretch Increases Cell Proliferation in Arteries in Organ Culture

Hai-Chao Han, Raymond P. Vito, Kristin Michael, David N. Ku
Proc. ASME. IMECE2000, Advances in Bioengineering, 63-64, November 5–10, 2000
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2000-2516
https://doi.org/10.1115/IMECE2000-2516
View Paper titled, Axial Stretch Increases Cell Proliferation in Arteries in Organ Culture
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Topics: Carotid arteries, Flow (Dynamics), Muscle, Physiology
Proceedings Papers

Design and Evaluation of Tissue Engineered Arteries

David N. Ku
Proc. ASME. IMECE2000, Advances in Bioengineering, 73, November 5–10, 2000
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2000-2521
https://doi.org/10.1115/IMECE2000-2521
View Paper titled, Design and Evaluation of Tissue Engineered Arteries
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Topics: Biological tissues, Design, Flow (Dynamics), Atherosclerosis, Diseases, Physiology, Testing
Proceedings Papers

Bench-Top Validation Tests for Tissue-Engineered Arteries

Shawn Chin Quee, Hai-Chao Han, David N. Ku
Proc. ASME. IMECE2000, Advances in Bioengineering, 59-60, November 5–10, 2000
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2000-2514
https://doi.org/10.1115/IMECE2000-2514
View Paper titled, Bench-Top Validation Tests for Tissue-Engineered Arteries
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Topics: Biological tissues, Physiology, Pressure, Flow (Dynamics), Mechanical properties, Testing
Proceedings Papers

CFD Model of Dynamic Thrombus Growth With and Without Shear Rate Dependant Deposition

David L. Bark, Jr., David N. Ku
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 529-530, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176667
https://doi.org/10.1115/SBC2007-176667
View Paper titled, CFD Model of Dynamic Thrombus Growth With and Without Shear Rate Dependant Deposition
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Topics: Computational fluid dynamics, Shear rate, Thrombosis, Platelets, Risk, Accidents, Adhesion, Atherosclerosis, Blood, Fluid mechanics
Proceedings Papers

Cyclic Bending of Coronary Plaques Leads to Much Higher Stress Variations: A Major Factor Contributing to Plaque Rupture Risk

Dalin Tang, Chun Yang, Jie Zheng, Shunichi Kobayashi, Gregorio A. Sicard, Pamela K. Woodard, David N. Ku
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 453-454, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-175454
https://doi.org/10.1115/SBC2007-175454
View Paper titled, Cyclic Bending of Coronary Plaques Leads to Much Higher Stress Variations: A Major Factor Contributing to Plaque Rupture Risk
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Topics: Risk, Rupture, Stress, Atherosclerosis, Fluid structure interaction, Coronary arteries, Flow (Dynamics), Fracture (Materials), Fracture (Process), Magnetic resonance imaging
Proceedings Papers

Effects of Channel Size and Shear Rate on Platelet Margination

Marmar Mehrabadi, Cyrus K. Aidun, David N. Ku
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT05A012, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14599
https://doi.org/10.1115/SBC2013-14599
View Paper titled, Effects of Channel Size and Shear Rate on Platelet Margination
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Topics: Atherosclerosis, Blood, Platelets, Risk, Shear rate, Thrombosis
Proceedings Papers

Shear Rate Characteristics of Growing Thrombus on a Stenosis in a Coronary Sized Vessel

David L. Bark, Jr., Andrea N. Para, David N. Ku
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1141-1142, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206766
https://doi.org/10.1115/SBC2009-206766
View Paper titled, Shear Rate Characteristics of Growing Thrombus on a Stenosis in a Coronary Sized Vessel
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Topics: Shear rate, Thrombosis, Vessels, Flow (Dynamics), Platelets, Shear (Mechanics), Atherosclerosis, Blood vessels
Proceedings Papers

Mechanical Testing of a New Prosthetic Anterior Cruciate Ligament Using Biocompatible Fibrous Hydrogel Constructs

Jason S. Bach, Fabrice Detrez, Frances R. Baxter, Sabine Cantournet, Mohammed Cherkaoui, Laurent Corté, David N. Ku
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1175-1176, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53286
https://doi.org/10.1115/SBC2011-53286
View Paper titled, Mechanical Testing of a New Prosthetic Anterior Cruciate Ligament Using Biocompatible Fibrous Hydrogel Constructs
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Topics: Anterior cruciate ligament, Artificial limbs, Biocompatibility, Hydrogels, Mechanical testing, Knee, Failure, Rupture, Creep, Fatigue
Proceedings Papers

Thrombus Initiation With Subsequent Growth Measured for Physiological Shear and High Pathological Shear

David L. Bark, Jr., Andrea N. Para, David N. Ku
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 23-24, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53865
https://doi.org/10.1115/SBC2011-53865
View Paper titled, Thrombus Initiation With Subsequent Growth Measured for Physiological Shear and High Pathological Shear
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Topics: Physiology, Shear (Mechanics), Thrombosis, Hemodynamics, Atherosclerosis, Diseases, Flow (Dynamics), Platelets, Rupture
Proceedings Papers

Computational Model of Thrombosis: A Study of Transport as a Determinant of Rapid Platelet Accumulation

David L. Bark, Jr., David N. Ku
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1095-1096, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53812
https://doi.org/10.1115/SBC2011-53812
View Paper titled, Computational Model of Thrombosis: A Study of Transport as a Determinant of Rapid Platelet Accumulation
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Topics: Platelets, Thrombosis, Adhesion, Atherosclerosis, Blood flow, Blood vessels, Risk
Journal Articles

Design Considerations for a Prosthetic Anterior Cruciate Ligament

Jason S. Bach, Mohammed Cherkaoui, Laurent Corté, Sabine Cantournet, David N. Ku
Journal: Journal of Medical Devices
Publisher: ASME
Article Type: Research-Article
J. Med. Devices. December 2012, 6(4): 045004.
https://doi.org/10.1115/1.4007945
Published Online: November 21, 2012
View Article titled, Design Considerations for a Prosthetic Anterior Cruciate Ligament
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Topics: Anterior cruciate ligament, Artificial limbs, Design, Knee, Prostheses, Bone, Tunnels, Testing, Stiffness