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Journal Articles

Kinesin and Dynein Mechanics: Measurement Methods and Research Applications

Zachary Abraham, Emma Hawley, Daniel Hayosh, Victoria A. Webster-Wood, Ozan Akkus
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Review Articles
J Biomech Eng. February 2018, 140(2): 020805.
Paper No: BIO-17-1289
https://doi.org/10.1115/1.4037886
Published Online: January 12, 2018
View Article titled, Kinesin and Dynein Mechanics: Measurement Methods and Research Applications
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Topics: Engines, Motors, Proteins, Microscopy
Includes: Supplementary data
Proceedings Papers

Feasibility of Portable Acoustic Emission Approach for Prognosis of Stress Fractures

Serife Agcaoglu, Vikas Kaul, Ozan Akkus
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 437-438, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192778
https://doi.org/10.1115/SBC2008-192778
View Paper titled, Feasibility of Portable Acoustic Emission Approach for Prognosis of Stress Fractures
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Topics: Acoustic emissions, Fracture (Materials), Fracture (Process), Stress, Bone, Magnetic resonance imaging, Computerized tomography, Damage, Diseases, Microscale devices
Proceedings Papers

Laboratory Modules for Reinforcement of Concepts Taught in Undergraduate Tissue Mechanics Course

Ozan Akkus, Allison Sieving
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 403-404, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192691
https://doi.org/10.1115/SBC2008-192691
View Paper titled, Laboratory Modules for Reinforcement of Concepts Taught in Undergraduate Tissue Mechanics Course
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Topics: Biological tissues, Undergraduate students, Stress, Anatomy, Musculoskeletal system, Statics, Strength (Materials), Biomechanics, Biomedical engineering, Physiology
Proceedings Papers

Improving the Anisotropy of Collagen by Electric Field Increases Its Toughness by Two-Fold

Xingguo Cheng, Nicholas Wasserman, Ozan Akkus
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1043-1044, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176705
https://doi.org/10.1115/SBC2007-176705
View Paper titled, Improving the Anisotropy of Collagen by Electric Field Increases Its Toughness by Two-Fold
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Topics: Anisotropy, Electric fields, Fracture toughness, Tendons, Biological tissues, Bone, Mechanical properties, Proteins, Skin
Proceedings Papers

An Implantable Magnetoelastic Sensor System for Wireless Physiological Sensing of Viscosity

Umut A. Gurkan, Ozan Akkus
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 759-760, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176707
https://doi.org/10.1115/SBC2007-176707
View Paper titled, An Implantable Magnetoelastic Sensor System for Wireless Physiological Sensing of Viscosity
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Topics: Physiology, Sensors, Viscosity, Bone, Pressure, Resonance, Signals, Temperature, Alloys, Biological tissues
Proceedings Papers

Measurement of Acoustic Emission Wave Attenuation by Bones and Muscles

Benjamin Pruden, Ozan Akkus
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 867-868, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-175825
https://doi.org/10.1115/SBC2007-175825
View Paper titled, Measurement of Acoustic Emission Wave Attenuation by Bones and Muscles
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Topics: Acoustic emissions, Bone, Muscle, Waves, Microcracks, Biological tissues, Fracture (Materials), Fracture (Process), Stress, Emissions
Proceedings Papers

A Practical Method for Real-Time Optical Imaging of Damage Zone and Microscale Failure in Bone

Jared J. Diegmueller, Ozan Akkus
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 967-968, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176714
https://doi.org/10.1115/SBC2007-176714
View Paper titled, A Practical Method for Real-Time Optical Imaging of Damage Zone and Microscale Failure in Bone
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Topics: Bone, Damage, Failure, Imaging, Microscale devices, Composite materials
Proceedings Papers

Electrochemical Compaction of the Collagen: Effects on Matrix Mechanics and MSC Response

Vipuil Kishore, Mousa Younesi, Stefi Panit, Ozan Akkus
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT02A005, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14361
https://doi.org/10.1115/SBC2013-14361
View Paper titled, Electrochemical Compaction of the Collagen: Effects on Matrix Mechanics and MSC Response
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Topics: Compacting, Matrix mechanics, Electrodes, Packing (Shipments), Packings (Cushioning), Biological tissues, Density, Disks, Fibers, Mechanical admittance
Proceedings Papers

Strength of Materials Based Prediction of Critical Stresses at the Proximal Femur: Validation by Finite Element Analysis

Andrew G. Tsai, Timothy Ashworth, Ozan Akkus
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT09A006, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14208
https://doi.org/10.1115/SBC2013-14208
View Paper titled, Strength of Materials Based Prediction of Critical Stresses at the Proximal Femur: Validation by Finite Element Analysis
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Topics: Finite element analysis, Strength (Materials), Stress, Failure, Fracture (Materials), Fracture (Process), Screws, Bone, Fatigue, Finite element methods
Proceedings Papers

Murine Osteochondral Stem Cells Express Collagen Type I More Strongly on PDMS Substrates Than on Tissue Culture Plastic

William S. Van Dyke, Ozan Akkus, Eric Nauman
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT17A008, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14272
https://doi.org/10.1115/SBC2013-14272
View Paper titled, Murine Osteochondral Stem Cells Express Collagen Type I More Strongly on PDMS Substrates Than on Tissue Culture Plastic
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Topics: Biological tissues, Plasma desorption mass spectrometry, Stem cells, Stiffness, Osteoblasts, Bone, Anchorage, Chondrocytes, Fibers, Stress
Proceedings Papers

Mechanical Stimulation Enhances the Production of BMP-2 in Ossifying Rat Bone Marrow Organ Cultures

Umut A. Gurkan, Adam Krueger, Ozan Akkus
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 295-296, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206745
https://doi.org/10.1115/SBC2009-206745
View Paper titled, Mechanical Stimulation Enhances the Production of BMP-2 in Ossifying Rat Bone Marrow Organ Cultures
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Topics: Bone, Biological tissues, Dynamics (Mechanics), Performance, Reservoirs, Stem cells
Proceedings Papers

Mechanically Induced Calcium Release From Bone Matrix Triggers Intracellular Ca 2+ Signalling in Osteoblasts: A Novel Mechanotransduction Mechanism

Xuanhao Sun, Vipuil Kishore, Kateri Fites, Ozan Akkus
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 333-334, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53446
https://doi.org/10.1115/SBC2011-53446
View Paper titled, Mechanically Induced Calcium Release From Bone Matrix Triggers Intracellular Ca 2+ Signalling in Osteoblasts: A Novel Mechanotransduction Mechanism
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Topics: Bone, Osteoblasts, Damage, Maintenance, Signals, Deformation, Fluid dynamics, Hydrostatic pressure, Microcracks, Shear (Mechanics)
Proceedings Papers

Incorporation of a Decorin Biomimetic Enhances the Mechanical Properties of Electrochemically Aligned Collagen Threads

Vipuil Kishore, John E. Paderi, Anna Akkus, Alyssa Panitch, Ozan Akkus
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 883-884, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53310
https://doi.org/10.1115/SBC2011-53310
View Paper titled, Incorporation of a Decorin Biomimetic Enhances the Mechanical Properties of Electrochemically Aligned Collagen Threads
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Topics: Biomimetics, Mechanical properties, Screw threads, Thread, Tendons, Chain, Anisotropy, Bearings, Biological tissues, Biomaterials
Proceedings Papers

A Novel Mechanical Bioreactor System Allowing Simultaneous Strain and Fluid Shear Stress on Cell Monolayers

W. Scott Van Dyke, Eric Nauman, Ozan Akkus
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1241-1242, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53595
https://doi.org/10.1115/SBC2011-53595
View Paper titled, A Novel Mechanical Bioreactor System Allowing Simultaneous Strain and Fluid Shear Stress on Cell Monolayers
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Topics: Bioreactors, Fluids, Shear stress, Bone, Fluid dynamics, Signals, Biology, Constitutive equations, Hydrostatic pressure, Osteoblasts
Proceedings Papers

Calcium Efflux From Bone Matrix in Response to Mechanical Loading

Xuanhao Sun, Eric S. McLamore, D. Marshall Porterfield, Ozan Akkus
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 505-506, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53625
https://doi.org/10.1115/SBC2011-53625
View Paper titled, Calcium Efflux From Bone Matrix in Response to Mechanical Loading
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Topics: Bone, Deformation, Fluids, Hydrostatic pressure, Maintenance, Shear (Mechanics)
Proceedings Papers

Modeling of Isoelectric Focusing of Type-I Collagen Molecules Under Uniform Electric Field

Jorge Alfredo Uquillas, Ozan Akkus
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1247-1248, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53185
https://doi.org/10.1115/SBC2011-53185
View Paper titled, Modeling of Isoelectric Focusing of Type-I Collagen Molecules Under Uniform Electric Field
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Topics: Electric fields, Modeling
Proceedings Papers

In Vivo Actuation System for Mechanostimulation of Large Wound Healing

Umut Atakan Gurkan, Alexandra Dubikovsky, Lynetta J. Freeman, Paul W. Snyder, Russell D. Meldrum, Ozan Akkus
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 605-606, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53183
https://doi.org/10.1115/SBC2011-53183
View Paper titled, In Vivo Actuation System for Mechanostimulation of Large Wound Healing
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Topics: Diabetes, Muscle, Pressure, Skin, Surgery, Tension, Wounds
Proceedings Papers

Changes in Turkey Femora Mechanical Properties Resulting From Selective Breeding for Body Weight

Ziwei Zhong, Serife Agcaoglu, Matthew Muckley, Hansi Zhao, Darrin Karcher, Michael Orth, Michael Lilburn, Ozan Akkus
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 897-898, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53115
https://doi.org/10.1115/SBC2011-53115
View Paper titled, Changes in Turkey Femora Mechanical Properties Resulting From Selective Breeding for Body Weight
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Topics: Bone, Dynamics (Mechanics), Failure, Fatigue, Maintenance, Mechanical properties, Microcracks, Safety, Stress, Weight (Mass)
Proceedings Papers

The Effect of Selective Breeding for Body Weight on Geometric Properties in Turkey Femurs

Matthew Muckley, Serife Agcaoglu, Ziwei Zhong, Hansi Zhao, Morgan Grisham, Darrin Karcher, Michael Orth, Michael Lilburn, Ozan Akkus
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 901-902, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53271
https://doi.org/10.1115/SBC2011-53271
View Paper titled, The Effect of Selective Breeding for Body Weight on Geometric Properties in Turkey Femurs
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Topics: Bone, Failure, Fatigue, Femoral fractures, Microcracks, Weight (Mass)
Journal Articles

Acoustic Emission Based Monitoring of the Microdamage Evolution During Fatigue of Human Cortical Bone

Serife Agcaoglu, Ozan Akkus
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2013, 135(8): 081005.
Paper No: BIO-12-1443
https://doi.org/10.1115/1.4024134
Published Online: June 12, 2013
View Article titled, Acoustic Emission Based Monitoring of the Microdamage Evolution During Fatigue of Human Cortical Bone
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Topics: Acoustic emissions, Bone, Emissions, Failure, Fatigue, Stress, Fracture (Materials), Fatigue life